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Creators/Authors contains: "Wang, Haoxuan"

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  1. Free, publicly-accessible full text available June 10, 2026
  2. Abstract An enantioselective synthesis of (−)‐10‐hydroxyacutuminine is reported. Central to our strategy is a photochemical [2+2] cycloaddition that forges two of the quaternary stereocenters present in the acutumine alkaloids. A subsequent retro‐aldol/Dieckmann sequence furnishes the spirocyclic cyclopentenone. Efforts to chlorinate the acutumine scaffold at C10 under heterolytic or radical deoxychlorination conditions led to the synthesis of an unexpected cyclopropane‐containing pentacycle. 
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